St. Charles is a community in Lee County, South Carolina, home to about 139 people across 4.2 square miles. It has no ZIP code of its own: it’s part of 29010 and 29104.
Homes sold for a median of $105 per square foot across 2 ZIP codes in the three months ending August 2026, and 1 of 2 were seller’s markets.
Part is in St. Charles, part in Bishopville and Manville
Mostly Mayesville; part is in St. Charles
Each card is that ZIP code’s whole market, including any part outside St. Charles. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up St. Charles’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Myrtle Beach International Airport (MYR)79 miles away |
|---|---|
| Closer regional airport | Florence Regional Airport (FLO)31 miles away |
| Nearest city of 250,000+ | Charlotte, NC88 miles away |
| Nearest city of 1 million+ | Philadelphia, PA500 miles away |
Straight-line distances from the center of St. Charles; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
It’s the 430th largest of 474 towns in South Carolina by population.
Lee County grew from 25,318 residents in 1910 to 16,531 in 2020.
Lee County, 1910–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 90°F in summer, and winter lows average 33°F. About 49 inches of rain and melted snow fall in a typical year, with about 0 inches of snow.
Source: NOAA 1991–2020 climate normals, Sumter, SC weather station (9 miles away).
2,246 jobs at 212 businesses in Lee County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
39 doctors and other health care providers list an office in St. Charles’s ZIP codes.
Nearest hospitals
Providers with an office here
| Primary care doctors | 7 |
|---|---|
| Dentists | 3 |
| Nurse practitioners and physician assistants | 8 |
| Mental health providers | 19 |
| Optometrists | 1 |
| Chiropractors | 1 |
| Pharmacies | 4 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Public schools here are run by Lee 01, SC Public Charter School District, Dept Of Correction N04. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Dennis ElementaryBishopville | Pre-K–5 | 359 | Public | 13.9 mi |
| Lower Lee ElementaryMayesville | Pre-K–5 | 128 | Public | 3.9 mi |
| Pee Dee Math Sci & TechBishopville | K–12 | 205 | Charter | 16.2 mi |
| Lee Central MiddleBishopville | 6–8 | 288 | Public | 10.8 mi |
| Lee Central HighBishopville | 9–12 | 402 | Public | 10.6 mi |
| Lee HighBishopville | 9–12 | 5 | Alternative Education | 11.8 mi |
| School | Grades | Students | Affiliation | Distance |
|---|---|---|---|---|
| Robert E Lee AcademyBishopville | Pre-K–12 | 283 | Christian (no specific denomination) | 13.5 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools; Private School Universe Survey (2023-2024) for private schools. Listed by address; we don’t rate schools.
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Shares ZIP codes with Bishopville, Mayesville, Manville, Elliott, Wisacky, Browntown and Ashwood.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.