Mayo is a community in Cherokee County, South Carolina, home to about 2,305 people across 3.0 square miles. Its ZIP code is 29368, and parts of 29323 and 29330 are in Mayo too.
Homes sold for a median of $172 per square foot across 2 ZIP codes in the three months ending August 2026, and 1 of 2 were seller’s markets.
All in Mayo
Part is in Mayo, part in Chesnee
Part is in Mayo, part in Cowpens
Each card is that ZIP code’s whole market, including any part outside Mayo. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Mayo’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Charlotte Douglas International Airport (CLT)52 miles away |
|---|---|
| Closer regional airport | Greenville-Spartanburg International Airport (GSP)24 miles away |
| Nearest city of 250,000+ | Charlotte, NC58 miles away |
| Nearest city of 1 million+ | Philadelphia, PA501 miles away |
Straight-line distances from the center of Mayo; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Mayo had 1,567 residents in the 2020 census, down 15% since 2000.
It’s the 181st largest of 474 towns in South Carolina by population.
Cherokee County grew from 21,359 residents in 1900 to 56,216 in 2020.
Cherokee County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 89°F in summer, and winter lows average 27°F. About 51.6 inches of rain and melted snow fall in a typical year, with about 1 inches of snow.
Source: NOAA 1991–2020 climate normals, Chesnee 7 Wsw, SC weather station (8 miles away).
17,983 jobs at 935 businesses in Cherokee County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
Nearest hospitals
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances.
Grocery stores
Libraries
Museums
Theaters and performance venues
Counts are within about 1.5 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Public schools here are run by Spartanburg 02. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Mayo ElementaryMayo | Pre-K–5 | 328 | Public | 2.2 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
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Shares ZIP codes with Cowpens and Chesnee.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.