Isle of Palms is a city in Charleston County, South Carolina, home to about 4,362 people across 4.4 square miles. Its ZIP code is 29451.
Homes sold for a median of $975 per square foot in the three months ending August 2026, a balanced market.
Each card is that ZIP code’s whole market, including any part outside Isle of Palms. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Isle of Palms’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Charleston International Airport (CHS)17 miles away |
|---|---|
| Nearest city of 250,000+ | Charlotte, NC177 miles away |
| Nearest city of 1 million+ | Philadelphia, PA561 miles away |
Straight-line distances from the center of Isle of Palms; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Isle of Palms had 4,347 residents in the 2020 census, down 5% since 2000.
It’s the 112th largest of 474 towns in South Carolina by population.
Charleston County grew from 88,006 residents in 1900 to 408,235 in 2020.
Charleston County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 91°F in summer, and winter lows average 37°F. About 51.6 inches of rain and melted snow fall in a typical year.
Source: NOAA 1991–2020 climate normals, Sullivans Is, SC weather station (5 miles away).
226,330 jobs at 15,801 businesses in Charleston County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
17 doctors and other health care providers list an office in Isle of Palms.
Nearest hospitals
Providers with an office here
| Primary care doctors | 3 |
|---|---|
| Specialist doctors | 2 |
| Dentists | 3 |
| Nurse practitioners and physician assistants | 1 |
| Mental health providers | 6 |
| Physical and occupational therapists | 2 |
| Pharmacies | 1 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (1 nearby)
Grocery stores (1 nearby)
Pharmacies
Libraries
Counts are within about 1.5 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.