Buffalo is a community in Union County, South Carolina, home to about 1,329 people across 4.0 square miles. Its ZIP code is 29321.
Homes sold for a median of $76 per square foot in the three months ending August 2026, a buyer’s market.
Each card is that ZIP code’s whole market, including any part outside Buffalo. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Buffalo’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Charlotte Douglas International Airport (CLT)54 miles away |
|---|---|
| Closer regional airport | Greenville-Spartanburg International Airport (GSP)33 miles away |
| Nearest city of 250,000+ | Charlotte, NC59 miles away |
| Nearest city of 1 million+ | Philadelphia, PA512 miles away |
Straight-line distances from the center of Buffalo; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Buffalo had 1,288 residents in the 2020 census, down 10% since 2000.
It’s the 237th largest of 474 towns in South Carolina by population.
Union County grew from 25,501 residents in 1900 to 27,244 in 2020.
Union County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 90°F in summer, and winter lows average 29°F. About 45.4 inches of rain and melted snow fall in a typical year, with about 2 inches of snow.
Source: NOAA 1991–2020 climate normals, Union 8 S, SC weather station (8 miles away).
5,632 jobs at 418 businesses in Union County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
2 doctors and other health care providers list an office in Buffalo.
Nearest hospitals
Providers with an office here
| Primary care doctors | 1 |
|---|---|
| Mental health providers | 1 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (2 nearby)
Grocery stores
Libraries
Museums
Counts are within about 1.5 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Public schools here are run by Union 01. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Buffalo ElementaryBuffalo | Pre-K–5 | 483 | Public | 1.5 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.