Greenville is a borough in Mercer County, Pennsylvania, home to about 5,523 people across 1.9 square miles. Its ZIP code is 16125.
Homes sold for a median of $67 per square foot in the three months ending August 2026, a seller’s market.
Mostly Greenville; also Hempfield Township and West Salem
Each card is that ZIP code’s whole market, including any part outside Greenville. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Greenville’s story and what everyday life there is like, for people thinking about moving in.
Are you a local agent who knows Greenville well? Agents who advertise here will be able to write the guide. Advertise on OfferBacked
| Nearest major airport | Pittsburgh International Airport (PIT)64 miles away |
|---|---|
| Closer regional airport | Erie International Tom Ridge Field (ERI)48 miles away |
| Nearest city of 250,000+ | Cleveland, OH68 miles away |
| Nearest city of 1 million+ | Philadelphia, PA291 miles away |
Straight-line distances from the center of Greenville; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Greenville had 5,540 residents in the 2020 census, down 13% since 2000.
It’s the 515th largest of 2,568 towns in Pennsylvania by population.
Mercer County grew from 57,387 residents in 1900 to 110,652 in 2020.
Mercer County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 81°F in summer, and winter lows average 16°F. About 43.8 inches of rain and melted snow fall in a typical year, with about 62 inches of snow.
Source: NOAA 1991–2020 climate normals, Jamestown 2 Nw, PA weather station (8 miles away).
40,948 jobs at 2,611 businesses in Mercer County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
149 doctors and other health care providers list an office in Greenville.
Nearest hospitals
Providers with an office here
| Primary care doctors | 17 |
|---|---|
| Specialist doctors | 25 |
| Dentists | 12 |
| Nurse practitioners and physician assistants | 29 |
| Mental health providers | 18 |
| Physical and occupational therapists | 39 |
| Optometrists | 1 |
| Chiropractors | 8 |
| Pharmacies | 10 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (4 nearby)
Grocery stores (2 nearby)
Pharmacies (2 nearby)
Libraries (2 nearby)
Museums (1 nearby)
Theaters and performance venues (1 nearby)
Counts are within about 1 mile of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Established in 1819.
Source: Wikidata (wikidata.org), the free knowledge base; people are listed by place of birth.
Public schools here are run by Greenville Area SD, Keystone Education Center CS, Reynolds SD. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Greenville El SchGreenville | K–6 | 626 | Public | 0.9 mi |
| Keystone Education Center CSGreenville | K–12 | 174 | Charter | 3.9 mi |
| Reynolds El SchGreenville | K–6 | 530 | Public | 4.9 mi |
| Greenville JSHSGreenville | 7–12 | 610 | Public | 0.2 mi |
| Reynolds JSHSGreenville | 7–12 | 426 | Public | 4.6 mi |
| School | Grades | Students | Affiliation | Distance |
|---|---|---|---|---|
| St Michael SchoolGreenville | Pre-K–7 | 44 | Roman Catholic | 1.2 mi |
| County Line SchoolGreenville | 1–8 | 23 | Amish | 6.0 mi |
| Meadow Valley Christian SchoolGreenville | 1–8 | 34 | Amish | 4.1 mi |
| Osborn SchoolGreenville | 1–8 | 22 | Amish | 5.4 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools; Private School Universe Survey (2023-2024) for private schools. Listed by address; we don’t rate schools.
Buying or selling around Greenville? Tell us what you need and when. No agents advertise here yet, so we’ll keep your request for up to 30 days and send it to local agents who join. No obligation, and you choose who to work with.
Loading map…
Shares ZIP codes with Hempfield Township, West Salem, Salem Township (Mercer County), Sugar Grove Township (Mercer County), Delaware Township (Mercer County) and Otter Creek.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.