Buffalo is a community in Guernsey County, Ohio, home to about 936 people across 0.5 square miles. Its ZIP code is 43722, and parts of 43780 are in Buffalo too.
Homes sold for a median of $67 per square foot in the three months ending August 2026.
Part is in Buffalo, part in Senecaville
Each card is that ZIP code’s whole market, including any part outside Buffalo. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
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| Nearest major airport | John Glenn Columbus International Airport (CMH)74 miles away |
|---|---|
| Closer regional airport | Mid Ohio Valley Regional Airport (PKB)40 miles away |
| Nearest city of 250,000+ | Columbus, OH79 miles away |
| Nearest city of 1 million+ | Philadelphia, PA337 miles away |
Straight-line distances from the center of Buffalo; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Buffalo had 373 residents in the 2020 census, down 7% since 2010.
It’s the 701st largest of 1,264 towns in Ohio by population.
Guernsey County grew from 34,425 residents in 1900 to 38,438 in 2020.
Guernsey County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 85°F in summer, and winter lows average 21°F. About 41.4 inches of rain and melted snow fall in a typical year, with about 17 inches of snow.
Source: NOAA 1991–2020 climate normals, Cambridge, OH weather station (8 miles away).
12,636 jobs at 828 businesses in Guernsey County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
2 doctors and other health care providers list an office in Buffalo.
Nearest hospitals
Providers with an office here
| Nurse practitioners and physician assistants | 1 |
|---|---|
| Mental health providers | 1 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Libraries
Counts are within about 1 mile of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
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Shares ZIP codes with Senecaville.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.