Syracuse is a city in Otoe County, Nebraska, home to about 1,990 people across 1.3 square miles. Its ZIP code is 68446.
Homes sold for a median of $127 per square foot in the three months ending August 2026, a seller’s market.
Each card is that ZIP code’s whole market, including any part outside Syracuse. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Syracuse’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Eppley Airfield (OMA)47 miles away |
|---|---|
| Closer regional airport | Lincoln Airport (LNK)33 miles away |
| Nearest city of 250,000+ | Lincoln, NE28 miles away |
| Nearest city of 1 million+ | Chicago, IL449 miles away |
Straight-line distances from the center of Syracuse; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Syracuse had 1,941 residents in the 2020 census, up 10% since 2000.
It’s the 63rd largest of 580 towns in Nebraska by population.
Otoe County grew from 22,288 residents in 1900 to 15,912 in 2020.
Otoe County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 88°F in summer, and winter lows average 13°F. About 32.3 inches of rain and melted snow fall in a typical year, with about 26 inches of snow.
Source: NOAA 1991–2020 climate normals, Syracuse, NE weather station (about a mile away).
5,041 jobs at 470 businesses in Otoe County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
24 doctors and other health care providers list an office in Syracuse.
Nearest hospitals
Providers with an office here
| Primary care doctors | 4 |
|---|---|
| Dentists | 2 |
| Nurse practitioners and physician assistants | 6 |
| Mental health providers | 4 |
| Physical and occupational therapists | 6 |
| Optometrists | 1 |
| Chiropractors | 1 |
| Pharmacies | 2 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (2 nearby)
Grocery stores (2 nearby)
Libraries (1 nearby)
Museums (1 nearby)
Counts are within about 1 mile of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Public schools here are run by Syracuse-Dunbar-Avoca Schools. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Elementary School at SyracuseSyracuse | Pre-K–3 | 277 | Public | 0.1 mi |
| Middle School at SyracuseSyracuse | 4–8 | 286 | Public | 0.3 mi |
| High School at SyracuseSyracuse | 9–12 | 228 | Public | 0.3 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.