Prairie Home is a city in Cooper County, Missouri, home to about 251 people across 0.4 square miles. Its ZIP code is 65068.
Homes sold for a median of $172 per square foot in the three months ending August 2026, a buyer’s market.
Each card is that ZIP code’s whole market, including any part outside Prairie Home. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Prairie Home’s story and what everyday life there is like, for people thinking about moving in.
Are you a local agent who knows Prairie Home well? Agents who advertise here will be able to write the guide. Advertise on OfferBacked
| Nearest major airport | Kansas City International Airport (MCI)118 miles away |
|---|---|
| Closer regional airport | Columbia Regional Airport (COU)20 miles away |
| Nearest city of 250,000+ | Kansas City, MO107 miles away |
| Nearest city of 1 million+ | Chicago, IL332 miles away |
Straight-line distances from the center of Prairie Home; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Prairie Home had 262 residents in the 2020 census, up 19% since 2000.
It’s the 676th largest of 1,060 towns in Missouri by population.
Cooper County grew from 22,532 residents in 1900 to 17,103 in 2020.
Cooper County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 88°F in summer, and winter lows average 20°F. About 42.7 inches of rain and melted snow fall in a typical year.
Source: NOAA 1991–2020 climate normals, Boonville, MO weather station (12 miles away).
3,868 jobs at 408 businesses in Cooper County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
2 doctors and other health care providers list an office in Prairie Home.
Nearest hospitals
Providers with an office here
| Mental health providers | 1 |
|---|---|
| Physical and occupational therapists | 1 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Public schools here are run by Prairie Home R-V. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Prairie Home Elem.Prairie Home | K–5 | 63 | Public | 0.7 mi |
| Prairie Home HighPrairie Home | 6–12 | 90 | Public | 0.7 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
Buying or selling around Prairie Home? Tell us what you need and when. No agents advertise here yet, so we’ll keep your request for up to 30 days and send it to local agents who join. No obligation, and you choose who to work with.
Loading map…
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.