Middletown is a town in Pike County, Missouri, home to about 248 people across 0.3 square miles. It has no ZIP code of its own: it’s part of 63359.
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| Nearest major airport | St. Louis Lambert International Airport (STL)60 miles away |
|---|---|
| Closer regional airport | Columbia Regional Airport (COU)49 miles away |
| Nearest city of 250,000+ | St. Louis, MO69 miles away |
| Nearest city of 1 million+ | Chicago, IL271 miles away |
Straight-line distances from the center of Middletown; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Middletown had 171 residents in the 2020 census, down 14% since 2000.
It’s the 678th largest of 1,060 towns in Missouri by population.
Pike County grew from 25,744 residents in 1900 to 17,587 in 2020.
Pike County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 86°F in summer, and winter lows average 19°F. About 41.4 inches of rain and melted snow fall in a typical year.
Source: NOAA 1991–2020 climate normals, Vandalia, MO weather station (15 miles away).
4,438 jobs at 395 businesses in Pike County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
Nearest hospitals
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.