Louisiana is a city in Pike County, Missouri, home to about 3,228 people across 3.1 square miles. Its ZIP code is 63353.
Homes sold for a median of $72 per square foot in the three months ending August 2026, a buyer’s market.
Each card is that ZIP code’s whole market, including any part outside Louisiana. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Louisiana’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | St. Louis Lambert International Airport (STL)60 miles away |
|---|---|
| Closer regional airport | Quincy Regional Airport Baldwin Field (UIN)36 miles away |
| Nearest city of 250,000+ | St. Louis, MO71 miles away |
| Nearest city of 1 million+ | Chicago, IL243 miles away |
Straight-line distances from the center of Louisiana; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Louisiana had 3,199 residents in the 2020 census, down 17% since 2000.
It’s the 192nd largest of 1,060 towns in Missouri by population.
Pike County grew from 25,744 residents in 1900 to 17,587 in 2020.
Pike County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 86°F in summer, and winter lows average 19°F. About 40.8 inches of rain and melted snow fall in a typical year, with about 16 inches of snow.
Source: NOAA 1991–2020 climate normals, Bowling Green 1 E, MO weather station (8 miles away).
4,438 jobs at 395 businesses in Pike County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
28 doctors and other health care providers list an office in Louisiana.
Nearest hospitals
Providers with an office here
| Primary care doctors | 6 |
|---|---|
| Specialist doctors | 5 |
| Dentists | 2 |
| Nurse practitioners and physician assistants | 4 |
| Mental health providers | 3 |
| Physical and occupational therapists | 6 |
| Chiropractors | 2 |
| Pharmacies | 3 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (6 nearby)
Grocery stores (1 nearby)
Pharmacies
Libraries
Counts are within about 1.5 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Established in 1816.
Notable people born here
Source: Wikidata (wikidata.org), the free knowledge base; people are listed by place of birth.
Public schools here are run by Boncl R-X, Louisiana R-II. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| BONCL Elem.Louisiana | Pre-K–8 | 39 | Public | 4.1 mi |
| Louisiana Elem.Louisiana | Pre-K–5 | 343 | Public | 0.6 mi |
| Louisiana MiddleLouisiana | 6–8 | 151 | Public | 0.4 mi |
| Louisiana HighLouisiana | 9–12 | 187 | Public | 0.4 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.