Clarksdale is a city in DeKalb County, Missouri, home to about 399 people across 0.3 square miles. Its ZIP code is 64430.
Homes sold for a median of $273 per square foot in the three months ending August 2026.
Mostly Clarksdale
Each card is that ZIP code’s whole market, including any part outside Clarksdale. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
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| Nearest major airport | Kansas City International Airport (MCI)37 miles away |
|---|---|
| Nearest city of 250,000+ | Kansas City, MO48 miles away |
| Nearest city of 1 million+ | Chicago, IL385 miles away |
Straight-line distances from the center of Clarksdale; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Clarksdale had 245 residents in the 2020 census, down 30% since 2000.
It’s the 576th largest of 1,060 towns in Missouri by population.
DeKalb County grew from 14,418 residents in 1900 to 11,029 in 2020.
DeKalb County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 87°F in summer, and winter lows average 16°F. About 37.2 inches of rain and melted snow fall in a typical year.
Source: NOAA 1991–2020 climate normals, Cosby 2w, MO weather station (9 miles away).
2,181 jobs at 231 businesses in DeKalb County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
Nearest hospitals
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances.
Parks (1 nearby)
Counts are within about 1 mile of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.