Chillicothe is a city in Livingston County, Missouri, home to about 8,923 people across 7.1 square miles. Its ZIP code is 64601, and parts of 64664 are in Chillicothe too.
Homes sold for a median of $108 per square foot in the three months ending August 2026, a seller’s market.
Mostly Chillicothe; also Avalon
Mostly Mooresville; part is in Chillicothe
Each card is that ZIP code’s whole market, including any part outside Chillicothe. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Chillicothe’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Kansas City International Airport (MCI)71 miles away |
|---|---|
| Closer regional airport | Kirksville Regional Airport (IRK)57 miles away |
| Nearest city of 250,000+ | Kansas City, MO71 miles away |
| Nearest city of 1 million+ | Chicago, IL337 miles away |
Straight-line distances from the center of Chillicothe; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Chillicothe had 9,107 residents in the 2020 census, up 2% since 2000.
It’s the 96th largest of 1,060 towns in Missouri by population.
Livingston County grew from 22,302 residents in 1900 to 14,557 in 2020.
Livingston County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 87°F in summer, and winter lows average 16°F. About 41.3 inches of rain and melted snow fall in a typical year, with about 14 inches of snow.
Source: NOAA 1991–2020 climate normals, Chillicothe 2s, MO weather station (2 miles away).
5,093 jobs at 391 businesses in Livingston County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
79 doctors and other health care providers list an office in Chillicothe.
Nearest hospitals
Providers with an office here
| Primary care doctors | 9 |
|---|---|
| Specialist doctors | 8 |
| Dentists | 9 |
| Nurse practitioners and physician assistants | 17 |
| Mental health providers | 15 |
| Physical and occupational therapists | 10 |
| Optometrists | 5 |
| Chiropractors | 6 |
| Pharmacies | 9 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (6 nearby)
Grocery stores (2 nearby)
Pharmacies (1 nearby)
Libraries (2 nearby)
Museums (1 nearby)
Theaters and performance venues (1 nearby)
Counts are within about 2 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Established in 1855.
Colleges and universities
Source: Wikidata (wikidata.org), the free knowledge base; people are listed by place of birth.
Public schools here are run by Chillicothe R-II, Mo Schls for the Sev Disabled. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Chillicothe ElemChillicothe | Pre-K–5 | — | Public | 2.1 mi |
| Verelle Peniston SchoolChillicothe | K–12 | 15 | Special Education | 0.7 mi |
| Chillicothe MiddleChillicothe | 6–8 | 354 | Public | 0.6 mi |
| Chillicothe HighChillicothe | 9–12 | 563 | Public | 1.7 mi |
| Grand River Technical Sch.Chillicothe | 9–12 | — | Career and Technical | 0.4 mi |
| School | Grades | Students | Affiliation | Distance |
|---|---|---|---|---|
| Bishop Hogan Memorial SchoolChillicothe | Pre-K–8 | 130 | Roman Catholic | 0.2 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools; Private School Universe Survey (2023-2024) for private schools. Listed by address; we don’t rate schools.
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Shares ZIP codes with Mooresville and Avalon.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.