Saltillo is a city in Lee County, Mississippi, home to about 4,952 people across 8.2 square miles. Its ZIP code is 38866.
Homes sold for a median of $148 per square foot in the three months ending August 2026, a seller’s market.
Mostly Saltillo; also Tupelo
Each card is that ZIP code’s whole market, including any part outside Saltillo. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Saltillo’s story and what everyday life there is like, for people thinking about moving in.
Are you a local agent who knows Saltillo well? Agents who advertise here will be able to write the guide. Advertise on OfferBacked
| Nearest major airport | Frederick W. Smith International Airport (MEM)87 miles away |
|---|---|
| Closer regional airport | Tupelo Regional Airport (TUP)10 miles away |
| Nearest city of 250,000+ | Memphis, TN89 miles away |
| Nearest city of 1 million+ | Dallas, TX479 miles away |
Straight-line distances from the center of Saltillo; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Saltillo had 4,922 residents in the 2020 census, up 45% since 2000.
It’s the 70th largest of 420 towns in Mississippi by population.
Lee County grew from 21,956 residents in 1900 to 83,343 in 2020.
Lee County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 90°F in summer, and winter lows average 32°F. About 58 inches of rain and melted snow fall in a typical year, with about 1 inches of snow.
Source: NOAA 1991–2020 climate normals, Tupelo 2, MS weather station (10 miles away).
47,607 jobs at 2,550 businesses in Lee County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
66 doctors and other health care providers list an office in Saltillo.
Nearest hospitals
Providers with an office here
| Primary care doctors | 8 |
|---|---|
| Dentists | 6 |
| Nurse practitioners and physician assistants | 18 |
| Mental health providers | 14 |
| Physical and occupational therapists | 17 |
| Optometrists | 3 |
| Pharmacies | 3 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (1 nearby)
Grocery stores (1 nearby)
Museums
Counts are within about 2 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Established in 1849.
Source: Wikidata (wikidata.org), the free knowledge base; people are listed by place of birth.
Public schools here are run by Lee County. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Saltillo Primary SchoolSaltillo | Pre-K–2 | 704 | Public | 1.9 mi |
| Saltillo Elementary SchoolSaltillo | 3–5 | 696 | Public | 1.3 mi |
| Saltillo High SchoolSaltillo | 9–13 | 939 | Public | 1.7 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
Buying or selling around Saltillo? Tell us what you need and when. No agents advertise here yet, so we’ll keep your request for up to 30 days and send it to local agents who join. No obligation, and you choose who to work with.
Loading map…
Shares ZIP codes with Tupelo.
Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.