Big Pine Key is a community in Monroe County, Florida, home to about 4,258 people across 10 square miles. Its ZIP code is 33043.
Homes sold for a median of $651 per square foot in the three months ending August 2026, a buyer’s market.
Each card is that ZIP code’s whole market, including any part outside Big Pine Key. Seller’s market: under 4 months of supply; buyer’s market: over 6. Methodology
We’re writing up Big Pine Key’s story and what everyday life there is like, for people thinking about moving in.
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| Nearest major airport | Miami International Airport (MIA)102 miles away |
|---|---|
| Closer regional airport | Key West International Airport (EYW)26 miles away |
| Nearest city of 250,000+ | Miami, FL104 miles away |
Straight-line distances from the center of Big Pine Key; driving is longer.
Source: Airports from OurAirports (scheduled passenger service); city centers and populations from the U.S. Census Bureau.
Source: Members of Congress from the congress-legislators project; districts from the Census Bureau’s relationship files; governor and mayor from Wikidata.
Big Pine Key had 4,521 residents in the 2020 census, down 10% since 2000.
It’s the 519th largest of 954 towns in Florida by population.
Monroe County grew from 18,006 residents in 1900 to 82,874 in 2020.
Monroe County, 1900–2020
Source: U.S. Census Bureau decennial censuses (counties 1900–1990 from the Bureau’s historical county file).
Average highs peak around 90°F in summer, and winter lows average 64°F. About 46.1 inches of rain and melted snow fall in a typical year.
Source: NOAA 1991–2020 climate normals, Bahia Honda Sp, FL weather station (5 miles away).
37,134 jobs at 4,154 businesses in Monroe County. The biggest industries by employees:
Source: U.S. Census Bureau County Business Patterns 2023 (private employers; jobs counted where people work).
20 doctors and other health care providers list an office in Big Pine Key.
Nearest hospitals
Providers with an office here
| Primary care doctors | 3 |
|---|---|
| Dentists | 3 |
| Nurse practitioners and physician assistants | 5 |
| Mental health providers | 4 |
| Physical and occupational therapists | 4 |
| Chiropractors | 1 |
| Pharmacies | 2 |
Source: Hospitals from CMS Hospital General Information (ratings are CMS overall star ratings); straight-line distances; providers from the CMS National Plan and Provider Enumeration System (NPPES), by practice address and primary specialty.
Parks (2 nearby)
Grocery stores (1 nearby)
Pharmacies (2 nearby)
Libraries (1 nearby)
Museums (1 nearby)
Counts are within about 2.5 miles of the center of town.
Source: Map data © OpenStreetMap contributors (openstreetmap.org/copyright), as mapped by volunteers; it can miss places or include closed ones.
Public schools here are run by Monroe. Check each district’s attendance zones for a specific address.
| School | Grades | Students | Type | Distance |
|---|---|---|---|---|
| Big Pine AcademyBig Pine Key | Pre-K–5 | 89 | Charter | 0.8 mi |
Source: U.S. Department of Education, NCES: Common Core of Data (2024-2025) for public schools. Listed by address; we don’t rate schools.
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Town boundaries don’t always match ZIP codes: a ZIP code can cross into neighboring towns, and a town can share a ZIP code with its neighbors. Facts describe the town itself; market figures describe whole ZIP codes.